Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent
Patent
1990-02-06
1992-04-07
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
In vivo diagnosis or in vivo testing
Magnetic imaging agent
436173, 514 12, 514 23, 514 54, 514 59, 514738, 514814, 424617, 424614, G01N 3100, G01N 2400, A61K 3170, A61K 3700
Patent
active
051026520
ABSTRACT:
This invention relates to compositions comprising a colloidal or particular metal oxide which are stabilized by low molecular weight carbohydrates. The carbohydrates are characterized by the fact that a) they are not retained on the surface of the metal oxide based on the equilibrium room temperature dialysis of about 2 ml of the metal oxide composition at 0.2 M metal concentration against deionized water; and b) they impart sufficient stability to the metal oxide compositions such that the compositions can withstand heat stress without perceptible aggregation as determined by a prescribed test procedure.
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Groman Ernest V.
Josephson Lee
Advanced Magnetics Inc.
Hollinden Gary E.
Hollrah Glennon H.
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