Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2005-04-12
2005-04-12
Weber, Jon (Department: 1653)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S023100, C530S300000, C530S350000, C530S359000, C435S440000, C435S441000
Reexamination Certificate
active
06878817
ABSTRACT:
Isolated polynucleotides encoding novel polypeptides which are capable of binding to native and methylated LDL (low density lipoprotein), the isolated polypeptides, called LBPs (LDL binding proteins), and biologically active fragments and analogs thereof, are described. Also described are methods for determining if an animal is at risk for atherosclerosis, methods for evaluating an agent for use in treating atherosclerosis, methods for treating atherosclerosis, and methods for treating a cell having an abnormality in structure or metabolism of LBP. Pharmaceutical compositions and vaccine compositions are also provided.
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Arjona Anibal A.
Law Simon W.
Lees Ann M.
Lees Robert S.
Boston Heart Foundation, Inc.
Fish & Richardson PC
Mitra Rita
Weber Jon
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