Low carryover pipette probe

Details Low carryover pipette probe Low carryover pipette probe

1993-06-14

1995-11-21

Czaja, Donald E.

Chemical apparatus and process disinfecting, deodorizing, preser

Control element responsive to a sensed operating condition

422 63, 422 99, 436 43, 436180, 7386401, 7386414, 7386421, B01L 302

Patent

active

054684536

ABSTRACT:
An improved pipette probe in an automated chemical analysis system is provided, along with a pipette tip wash protocol to reduce carryover. The pipette tip comprises an elongated stainless-steel barrel which houses a polytetrafluoroethylene tube. The non-wettable properties of polytetrafluoroethylene inhibit fluid adhesion and thereby reduce carryover. The pipette tip is swaged at a fluid dispensing end to a restrictive diameter for good pipetting precision and accuracy. A novel wash protocol is also provided which includes a novel wash solution comprising quantities of Triton X-100 nonionic detergent, Diethanolamine, and NaCl.

REFERENCES:
patent: 3754444 (1973-08-01), Ure et al.
patent: 4312591 (1982-01-01), Tomoff
patent: 4326851 (1982-04-01), Bello et al.
patent: 4341736 (1982-07-01), Drbab et al.
patent: 4818870 (1989-04-01), Griffiths
patent: 5158748 (1992-10-01), Obi et al.
patent: 5260030 (1993-11-01), DeVaughn
patent: 5264182 (1993-11-01), Sakagami

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