Loracarbef isopropanolate

Details Loracarbef isopropanolate Loracarbef isopropanolate

1994-12-01

1997-09-30

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D48704, A61K 31435

Patent

active

056727003

ABSTRACT:
The invention is directed to the crystalline isopropyl alcohol solvate of loracarbef, and also is directed to a process for the preparation of the crystalline monohydrate form of the compound of formula (I) ##STR1## which includes exposing the crystalline isopropyl solvate form of the compound of formula (I) to a temperature of between about 50.degree. and 90.degree. C. and a relative humidity of between about 60 to about 100%.

REFERENCES:
patent: 3502663 (1970-03-01), Barnes
patent: 3531481 (1970-09-01), Pfeiffer
patent: 4977257 (1990-12-01), Eckrich et al.
patent: 5352782 (1994-10-01), Nist et al.
patent: 5399686 (1995-03-01), Henning et al.

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