Long wavelength ultraviolet ray absorber

Drug – bio-affecting and body treating compositions – Topical sun or radiation screening – or tanning preparations

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424DIG5, 424 47, 424 63, 424 64, 424 69, 514845, 514846, 514937, 514938, 514941, A61K 7021, A61K 7027, A61K 742, A61K 910

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047103736

ABSTRACT:
A composition for application to the skin to protect the skin from the long wavelength ultraviolet ray comprises a dibenzoylmethane derivative of the following general formula ##STR1## in which X represents a hydrogen atom, a monovalent metal cation, an organic cation, a linear or branched alkyl group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide having 2 or 3 carbon atoms, Y and Z each independently represent a hydroxyl group, a linear or branched alkyl group having from 1 to 24 carbon atoms, or an alkoxy group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide group having from 2 to 3 carbon atoms, and m and n are independently an integer of from 0 to 3.
The composition is adjustable so as to have an optimum HLB balance and has good compatibility with various cosmetic bases. Further, it does not irritate the skin, is difficult to be percutaneously absorbed and shows continued skin-protecting effects.

REFERENCES:
patent: 4381360 (1983-04-01), Leistner et al.
patent: 4489057 (1984-12-01), Welters et al.
Troeltzsch, Chem. Abs., 1964, vol. 60, p. 7947e.
Wurm et al, Chem. Abs., 1977, vol. 87, p. 22971r.
Yamane et al, Chem. Abs., 1960, vol. 56, p. 9416f.
Tolmachev et al, Chem. Abs., 1968, vol. 69, p. 106444n.
DeMent Abstract, O.G. 10/28/52, vol. 663, p. 1221.
Geissler et al, Chem. Abs; 1983, vol. 98, 174687t.

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