Long-term stable pharmaceutical preparation containing the...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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Reexamination Certificate

active

07872049

ABSTRACT:
A pharmaceutical preparation containing the active substance glyceryl trinitrate having improved storage stability in a container. The improved storage stability is achieved by the addition of a proton-absorbing substance either as part of the preparation as placed into the container or applied to the surface of the preparation's storage container before the remaining components of the preparation are placed into the container. The preparation can preferably be filled into a plastic bottle having a spray pump.

REFERENCES:
patent: 4919919 (1990-04-01), Aouda
patent: 5186925 (1993-02-01), Cholcha
patent: 5744124 (1998-04-01), Klokkers-Bethke
patent: 2003/0095925 (2003-05-01), Dugger
patent: 2004/0228883 (2004-11-01), Karl
patent: 2006/0003011 (2006-01-01), Crew
patent: 2007/0059346 (2007-03-01), Maibach
patent: 202008007318 (2008-09-01), None
patent: WO99/38472 (1999-08-01), None
patent: 2007123955 (2007-11-01), None
Nitrolingual Pumpspray product insert (nitroglycerin lingual spray), G. Pohl-Boskamp GmbH & Co. KG, Oct. 2008, 4 pages.
Nitrolingual Pumpspray package labelling (nitroglycerin lingual spray), G. Pohl-Boskamp GmbH & Co. KG, Nov. 2008, 1 page.
Nitrolingual Pumpspray bottle labelling (nitroglycerin lingual spray), G. Pohl-Boskamp GmbH & Co. KG, May 2006, 2 pages.

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