Long lifetime anisotropy (polarization) probes for clinical chem

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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Details

435 793, 436546, 436164, 436172, G01N 3353, G01N 33533, G01N 33536

Patent

active

056609914

ABSTRACT:
A method of conducting an immunoassay of a sample of interest is described, including the steps of (A) coupling a luminescent asymmetric metal-ligand complex to the sample of interest to form a coupled sample, (B) exciting the coupled sample with linearly polarized electromagnetic energy to cause the coupled sample to emit fluorescent light; and (C) measuring the polarization of the fluorescent emission as a measure of a biological characteristic of the sample of interest.

REFERENCES:
patent: 4816419 (1989-03-01), Halfman
patent: 5239057 (1993-08-01), Wang et al.

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