Long chain carboxylic acid imide ester

Details Long chain carboxylic acid imide ester Long chain carboxylic acid imide ester

1997-05-01

1999-10-26

Higel, Floyd D.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530410, 546243, 548431, 548435, 548475, 548514, 548542, 548548, C07K 100, C07K 1700, C07K 1600, C07K 1400, C07D20746, C07D21194

Patent

active

RE0363596

ABSTRACT:
Provided is a long chain carboxylic acid imide ester (I) represented by the following general formula (I) ##STR1## wherein W is a divalent long chain hydrocarbon group which may optionally be interrupted by one or more groups each independently selected from the group consisting of an oxygen, atom, a sulfur atom, and a group of --N(R.sup.1)-- (R.sup.1 being a lower alkyl group) and X represents a divalent hydrocarbon group which may optionally be substituted, or salt thereof. The above long chain carboxylic acid imide ester or its salts is useful for modifying enzymes or proteins having biological activities to give their derivatives which have, while retaining most of the original biological activities, an extremely prolonged plasma half-life as compared with the proteins and have no antigenecities and can be administered to animals.

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