Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1974-10-29
1977-08-09
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125S, A61K 3700, C07C10352
Patent
active
040411559
ABSTRACT:
An aqueous vehicle containing about 80% polyethylene glycol 400 or polyethylene glycol 300 imparts long-acting growth hormone release inhibiting activity to somatostatin or linear somatostatin.
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Gerich et al.: New Eng. J. Med., 291, 544-547 (1974).
Rivier: J. Am. Chem. Soc., 96, 2986-2992 (1974).
Sollmann, "Manual of Pharmacology," 8th ed., W. B. Saunders Co., Phila., 1957, pp. 128-130.
Brazeau et al.: Science, 179, 77-79 (1973).
Fenichel Richard L.
Levin Howard J.
American Home Products Corporation
Frankhouser David E.
Phillips Delbert R.
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