Long acting, reversible veterinary sedative and analgesic...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C514S398000

Reexamination Certificate

active

07074834

ABSTRACT:
A veterinary composition comprising a guanidine derivative, e.g., guanabenz or guanabenz acetate is provided which produces a rapid acting and long lasting sedative and analgesic effect in a subject animal that is selectively reversible. The use of guanabenz in the horse provides for a safe, effective, long lasting and rapidly reversible sedative and analgesic which can be used on the standing animal. Methods of use of the compositions of the invention are also provided.

REFERENCES:
patent: 4060640 (1977-11-01), Kodama et al.
patent: 4742054 (1988-05-01), Naftchi
patent: 4950648 (1990-08-01), Raddatz et al.
patent: 5635204 (1997-06-01), Gevirtz et al.
patent: 5942241 (1999-08-01), Chasin et al.
patent: 5958933 (1999-09-01), Naftchi
MEDLINE AN 20000025586, Veveris et al, Brit. J. Pharmacol, 128 (5), 1089-97, Nov. 1999, abstract.
Veterinary Pharmacology and Therapeutics, Adams, pp. 160-161, 1995.
Guanabenz (Wytensin), Prescription Drug Referene from Health Square.com, May 18, 2001.

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