Long-acting diclofenac sodium preparation

Details Long-acting diclofenac sodium preparation Long-acting diclofenac sodium preparation

1989-05-17

1990-11-06

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

424458, 424461, 424462, 424493, 424494, 424495, 424497, 424498, A61K 900

Patent

active

049685058

ABSTRACT:
A long-acting diclofenac sodium preparation is disclosed. The preparation comprises a sustained-release diclofenac sodium component which is prepared by coating a sustained-release coat onto a pharmaceutical composition comprising diclofenac sodium and an organic acid. It can decrease the maximum blood concentration of diclofenac by suppressing and controlling the rate of release of diclofenac sodium and maintain the blood concentration of diclofenac constant for a considerably long period of time. The risk of side-effect occurrences is reduced and patients is released from frequent administration of the medicine.

REFERENCES:
patent: 4726951 (1988-02-01), Panoz et al.
patent: 4814183 (1989-03-01), Zentner

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