Lock and key micelles

Details Lock and key micelles Lock and key micelles

1994-07-25

1997-07-22

Lovering, Richard D.

Plastic and nonmetallic article shaping or treating: processes

Encapsulating normally liquid material

Liquid encapsulation utilizing an emulsion or dispersion to...

252312, 424 153, 424497, 424DIG16, 42840221, 42840222, 525903, 525936, A61K 9107, A61K 950, B01J 1320, B01J 1322

Patent

active

056501013

ABSTRACT:
A lock unimolecular micelle includes at least one engineered acceptor specifically binding a ligand (or specifically a "key" unimolecular micelle) thereto. A key unimolecular micelle comprises a core molecule and a plurality of branches extending therefrom, at least one of the branches including a shank portion extending therefrom having a terminal moiety at an end thereof for binding to a complimentary acceptor of a lock unimolecular micelle. Together, the lock and key micelles form a unit, either irreversibly or reversibly bound wherein the lock micelles is a soluble receptor engineered to specifically bind to the specifically engineered key micelle.

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