Localized two-dimensional shift correlated MR spectroscopy...

Details Localized two-dimensional shift correlated MR spectroscopy... Localized two-dimensional shift correlated MR spectroscopy...

2007-04-03

2007-04-03

Casler, Brian L. (Department: 3737)

Surgery

Diagnostic testing

Detecting nuclear, electromagnetic, or ultrasonic radiation

C600S407000, C600S413000

Reexamination Certificate

active

10221385

ABSTRACT:
A two-dimensional (2D) chemical shift correlated MR spectroscopic (COSY) sequence integrated into a new volume localization technique (90°-180°-90°) for whole body MR Spectroscopy. Using the product operator formalism, a theoretical calculation of the volume localization as well as the coherence transfer efficiencies in 2D MRS is presented. A combination of different MRI transmit/receive rf coils is used. The cross peak intensities excited by the proposed 2D sequence are asymmetric with respect to the diagonal peaks. Localized COSY spectra of cerebral frontal and occipital gray/white matter regions in fifteen healthy controls are presented.

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