Localized intravascular delivery of growth factors for promotion

Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...

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A61M 3100

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active

059418680

ABSTRACT:
Angiogenesis in cardiac and other tissues is promoted by the transmural delivery of angiogenic factors such as VEGF, FGF, EGF, and PDGF, through blood vessels and other body lumens into the surrounding tissue. Usually, the angiogenic factor is delivered using a catheter having infusion parts at its distal end. Optionally, the distal end of the catheter is radially expanded to engage the infusion parts directly against the blood vessel wall.

REFERENCES:
patent: 5021044 (1991-06-01), Sharkawy
patent: 5049132 (1991-09-01), Shaffet et al.
patent: 5171217 (1992-12-01), March et al.
patent: 5180366 (1993-01-01), Woods
patent: 5244460 (1993-09-01), Unger et al.
patent: 5652225 (1997-07-01), Isner
Whalen, G. F. et al. "The Fate of Intravenously Administered bFGF and the Effect of Heparin," (1989) Growth Factors, vol. 1, pp. 157-164.
Cuevas, P. et al. "Single Topical Application of Human Recombinant Basic Fibroblast Growth Factor (rbFGF) Promotes Neovascularization in Rat Cerebral Cortex," (1993) Surg Neurol, vol. 39, pp. 380-384.
Edelman, E. R. et al. "Perivascular and Intravenous Administration of Basic Fibroblast Growth Factor: Vascular and Solid Organ Deposition," (1993) Proc Natl Acad Sci USA, vol. 90, pp. 1513-1517.
Battler, A. et al. "Intracoronary Injection of Basic Fibroblast Growth Factor Enhances Angiogenesis in Infarcted Swine Myocardium," (1993) JACC, vol. 22, No. 7, pp. 2001-2006.
Sellke, F. W. et al. "Basic FGF Enhances Endothelium-Dependent Relaxation of the Collateral-Perfused Coronary Microcirculation," (1994) American Physiological Society, pp. H1303-H1311.
Riessen, R. et al. "Prospects for Site-Specific Delivery of Pharmacologic and Molecular Therapies," (1994) JACC, vol. 23, No. 5, pp. 1234-1244.
Harada, K. et al. "Basic Fibroblast Growth Factor Improves Myocardial Function in Chronically Ischemic Porcine Hearts," (1994) J Clin Invest, vol. 94, pp. 623-630.

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