Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1982-08-26
1985-07-16
Ore, Dale R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
424 28, 424 47, 424 65, 424 68, 514817, A61K 732, A61K 912, A61K 970, A61K 31245
Patent
active
045296014
ABSTRACT:
The present invention relates to pharmacological active preparations, especially local anesthetic preparations and deals with the problem of i a obtaining a solution of a local anesthetic agent in the form of its base, where the concentration is higher than otherwise possible. This problem has been dissolved according to the present invention thereby that one local anesthetic agent in the form of its base and as such having a melting point of 30.degree. to 50.degree. C., preferably prilocaine or tetracaine, is provided with one other local anesthetic agent in the form of its base and as such having a melting point of above 30.degree. C., preferably above 40.degree. C., preferably bensocaine, lidocaine, bupivacaine, mepivacaine, etidocaine or tetracaine which agents when brought and heated together form a homogenous oil having a melting of preferably below 40.degree. C., more preferably below 25.degree. C.
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Chemical Abstracts, 1961, vol. 55, 10803-6, Rote Liste 1971, "Sprucaine Spray".
Broberg Berndt F. J.
Evers Hans C. A.
Astra Lakemedel Aktiebolag
Ore Dale R.
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