Local anesthetic methods and kits

Drug – bio-affecting and body treating compositions – Enzyme or coenzyme containing – Hydrolases

Reexamination Certificate

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C514S537000, C514S649000

Reexamination Certificate

active

11081640

ABSTRACT:
Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing anesthesia with a low dose of an alpha adrenergic receptor antagonist. Also disclosed are kits comprising a local anesthetic, an alpha adrenergic receptor agonist and a low dose of an alpha adrenergic receptor antagonist.

REFERENCES:
patent: 4197301 (1980-04-01), Smith et al.
patent: 4508715 (1985-04-01), Booth et al.
patent: 4659714 (1987-04-01), Watt-Smith
patent: 4888344 (1989-12-01), Sunagawa et al.
patent: 4938870 (1990-07-01), Butler et al.
patent: 5149320 (1992-09-01), Dhaliwal et al.
patent: 5192527 (1993-03-01), Abrahmsohn
patent: 5236904 (1993-08-01), Gerstenberg et al.
patent: 5261903 (1993-11-01), Dhaliwal et al.
patent: 6001845 (1999-12-01), Estok
patent: 6432401 (2002-08-01), Weber et al.
patent: 6764678 (2004-07-01), Weber et al.
patent: 6872390 (2005-03-01), Weber et al.
patent: 2004/0063747 (2004-04-01), Weber et al.
patent: 2004/0198816 (2004-10-01), Weber et al.
patent: WO99/30718 (1999-06-01), None
patent: WO99/43354 (1999-09-01), None
Edwall, B., et al., “Neuropeptide Y (NPY) and sympathetic control of blood flow in oral mucosa and dental pulp in the cat,”Acta Physiol. Scand. 125:253-264, Blackwell Scientific Publications (1985).
Koss, M.C., “Differential neural activation of vascular α-adrenoceptors in oral tissues of cats,”Eur. J. Pharmacol. 440:53-59, Elsevier Science B.V. (Apr. 2002).
Bernstein R.M., and Rassman, W.R., “Limiting epinephrine in large hair transplant sessions,”Hair Transplant Forum International 10:39-42, New Hair Institute, Inc. (Mar.-Apr. 2000), accessed on Aug. 23, 2002, available at: <http://www.800newhair.com/medical—publications/limiting—epinephrine.html>.
Pimentel, L.A.S., and Goldenburg, R.C.D.S., “Local Injection of Hyaluronidase in Increasing Skin Flap Survival: An Experimental Study,”Revista da Sociedade Brasileira de Cirurgia Plastica 14:49-55, Sociedade Brasileira de Cirurgia Plastica (1999), accessed on Aug. 15, 2000, available at: http://www.sbcp.org/revista/vol14—n1/pimentel/english.html>.
Robertson, V.J., et al., “Quantitative and qualitative analysis of the pressor effects of levonordefrin,”J. Cardiovasc. Pharmacol. 6:929-935, Lippincott, Williams, & Wilkins (1984).
Swinyard, E.A., “Local Anesthetics,” inRemington's Pharmaceutical Sciences, Osol, A. et al., eds., Mack Publishing Co., Easton, PA, pp. 991-1003 (1980).
International Search Report for International Application No. PCT/US01/40711, mailed Oct. 11, 2001.
Supplementary European Search Report for European Patent Application No. EP 01 93 3419, completed on Mar. 21, 2005, European Patent Office, Munich, Germany.
Crawford, R.A., et al., “The response of feline spinal pial arterioles to norepinephrine,”J. Neurosurg. 52:60-63, American Association of Neurological Surgeons (1990).

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