Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Reexamination Certificate
2005-02-01
2005-02-01
Gambel, Phillip (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
C424S130100, C424S133100, C424S141100, C424S143100, C424S144100, C424S153100, C424S173100, C530S387100, C530S387300, C530S388100, C530S388200, C530S388220, C530S388700, C530S388730, C530S388750, C435S326000, C435S328000, C435S332000, C435S343000, C435S343100, C435S343200, C435S346000
Reexamination Certificate
active
06849258
ABSTRACT:
The present invention relates to a LO-CD2a antibody and methods of using such antibodies or molecules that bind to the same epitope (or a portion thereof) to prevent and inhibit an immune response in human patients, preferably, where the immune response is mediated by the activation and proliferation of T cells or natural killer cells. The administration of an effective amount of the LO-CD2a antibody to a human patient will prevent or inhibit graft rejection, graft versus host disease or autoimmune disease.
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Bazin Herve
Kaplan Ruth
Kieber-Emmons Thomas
Latinne Dominique
Postema Christina E.
BioTransplant, Inc.
Gambel Phillip
Lillie Raymond J.
Olstein Elliot M.
Universite Catholique de Louvain
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