Liver stem cell

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell

Reexamination Certificate

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Details

C424S093100, C435S001100, C435S325000

Reexamination Certificate

active

06872389

ABSTRACT:
The invention provides methods of isolating a primary liver stem cell by identifying a cell doublet containing a hepatocytes and the stem cell and isolating the doublet from liver tissue.

REFERENCES:
patent: 5861313 (1999-01-01), Pang et al.
patent: 6129911 (2000-10-01), Faris
patent: 9303142 (1993-02-01), None
Malcolm Alison, Liver Stem cells: a two compartment system (1998).*
Stewart Sell- Is there a liver Stem Cell? (1990).*
Maria Agelli—Putative liver progenitor cells: conditions for long-term survival in culture (1992).*
Yan-Wu Tian- The oval-shaped cell as a candidate for a liver stem cell in embryonic, neonatal and precancerious liver: identification based on morphology and immunohistochemical staining for albumin and pyruvate kinase isoenyzme expression.*
Joan M. Lemire- Oval cell proliferation and a origin of small hepatocytes in Liver injury induced by d-galactosamine (1991).*
Malcolm Alison—Wound healing in the liver with particular reference to stem cells (1998).*
Shlomo-Brill- Hepatic progenitor populations in Emryonic, Neonatal, and Adult Liver (1993).

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