Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1994-11-30
1995-12-26
Criares, T. J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514120, 514148, 514458, 514893, A61K 31665, A61K 3166, A61K 31355
Patent
active
054788153
ABSTRACT:
A liver protectant comprising a phosphoric diester compound of the following formula (wherein R.sub.1 and R.sub.2 are the same or different and each represents hydrogen or methyl) or a pharmacologically acceptable salt thereof. ##STR1## The liver protectant composition of this invention effectively inhibits the elevation of GOT and GPT, among other parameters, so that it is useful for the prevention and therapy , of acute liver disorder, chronic liver disorder and fuminant liver disorder. It can also be used in cirrhosis of the liver with success. The liver protectant composition of this invention can be used with advantage in liver damage associated with alcohol intake and hepatic impairment due to acetaminophen and other drugs. Furthermore, the liver protectant composition of this invention is of value in acute intrahepatic cholestasis.
REFERENCES:
patent: 4888329 (1989-12-01), Ogata et al.
patent: 5306713 (1995-04-01), Suetsugu et al.
Matsuura Sachiko
Nagao Rie
Ogata Kazumi
Ogino Shinya
Sakaue Takahiro
Criares T. J.
Senji Pharmaceutical Co., Ltd.
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