Live vaccine for contagious diseases of chickens

Drug – bio-affecting and body treating compositions – Lymphokine

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435235, 435236, 435237, 435238, 435239, A61K 3912, C12N 700

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active

049801627

ABSTRACT:
A live vaccine for infectious laryngotracheitis, which comprises culture cells infected with attenuated infectious laryngotracheitis virus. Also, a live combined vaccine for infectious laryngotracheitis and Marek's disease, which comprises culture cells infected with attenuated viruses off these two diseases. These vaccines can be used on day-old (newborn) chicken, by subcutaneous or intramuscular injection, to give them immunity from infection by the virus or viruses.

REFERENCES:
patent: 3642574 (1972-02-01), Okazaki et al.
patent: 3981771 (1976-09-01), Sevoian et al.
Japanese Pat. No. 57,167,925 (82,167,925), "Preparation of mixed vaccines om the control of diseases in chickens", Chemical Abstracts, vol. 98, p. 341, Ref. #22260k, 1983.
Rossi et al, "Studies of Laryngotra cheitis virus in avian tissue cultures III. Enhancement of infectivity by DEAE-D," Chemical Abstracts, vol. 73, p. 91, ref. #5325x, 1970.
Shornikov et al, "lysozyrme activity of blood serum of chicks vaccinated agaisnt ILT by inhalation method," Chemical Abstracts, vol. 84, p. 246, ref. #71789j, 1976.
Hirai et al, "Comparative Studies on Marek's Disease Virus and Herpesvirus of Turkey DNAS," J. gen. Virol. vol. 45, pp. 119-131, 1979.
Van Zaane et al, "Molecular-Biological characterization of Marek's disease virus," Virology, vol. 121, pp. 133-146, 1982.
Gibbs et al, "Extensive homology exists between marek's disease herpesvirus and its vaccine virus, herpesvirus of turkeys," Proe. Natl. Acad. Sci., U.S.A., vol. 81, pp. 3365-3369, 1984.
Davis et al, "Ultrastructural Comparison of Morphogenesis and fate of Marek's disease and Inafectious Laryngotrocheitas Viruses in chicken Kidney Cells" Amer. J. Vet. Res. 34 (7): 873-880, Jul. 1973.
"Immunication Against Marek's Disease Using A Live Attenuated Virus", Churchill et al., Nature, vol. 221, pp. 744-747 (Feb. 22, 1969).

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