Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1994-12-30
1998-11-03
Minnifield, N. M.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4242001, 4241851, 4241971, 4242101, 4241921, 4241841, 4242091, 435 697, 4351723, 435822, 4353201, 536 231, 536 234, 536 2372, 514 2, 935 27, 935 23, C07H 2104, C12N 1563, A61K 3900, C12P 2106
Patent
active
058307028
ABSTRACT:
Vaccines comprising an attenuated strain of Listeria spp. expressing a selected foreign antigen and methods of eliciting protective immunity by administering an effective amount of the vaccine are provided. The vaccines of the present invention are designed specifically to elicit strong cell-mediated immunity, and are particularly useful for protection in infections which can apparently persist and spread in the presence of neutralizing antibodies invoked by humoral immunity.
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Paterson Yvonne
Portnoy Daniel A.
Minnifield N. M.
The Trustees of the University of Pennsylvania
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