Live attenuated human rotavirus vaccine

Details Live attenuated human rotavirus vaccine Live attenuated human rotavirus vaccine

1985-02-08

1986-11-25

Rosen, Sam

Drug, bio-affecting and body treating compositions

Lymphokine

435237, 435235, A61K 3912

Patent

active

046248501

ABSTRACT:
This invention provides a live attenuated human rotavirus vaccine and a method for the preparation of such a vaccine. The method overcomes problems experienced hitherto in the growth of human rotaviruses, by the use of larger quantities of inocula at the initial growth stage and subsequent passages.

REFERENCES:
Babiuk et al. -Chem. Abst. vol. 88 (1978) p. 71141z.
Albert, M. J., et al., J of Clin Microbiol (1983) 17:162-164.
Babiuk, I. A., et al., J of Clin Microbiol (1977) 6:610-617.
Dyall-Smith, M. L., et al., Nucleic Acids Res (1984) 12:3973.
Faulkner-Valle, G. P., et al., J of Virol (1982) 42:669-677.
Bishop, R. F., et al., The Lancet (1974) Feb., pp. 149-151.
Kutsuzawa, T., et al., J of Clin Microbiol (1982) 16:727-730.
Laemmli, U. K., Nature (1970) 227:680-685.
Rodger, S. M., et al., J. Clin Microbiol (1981) 13:272-278.
Rodger, S. M., et al., "Comparison of the Genomes of Simian, Bovine and Human Rotaviruses by Gel Electrophoresis and the Detection of Genomic Variation Amongst Bovine Isolates" (in press).
Sato, K., et al., Archives of Virology (1981) 69:155-160.
Whitby, H. J., et al., J Clin Pathol (1980) 33:484-487.
Urasawa, T., et al., Microbiol Immunol (1981) 25(10):1025-1035.
Who Expert Comm. on Biological Standardization, 33rd Report (Technical Report Series 687), Who:Geneva, 1983.

Affiliated with

Also associated with

Rating

Live attenuated human rotavirus vaccine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Live attenuated human rotavirus vaccine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Live attenuated human rotavirus vaccine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1157764