Lithographic mask design and synthesis of diverse probes on a su

Details Lithographic mask design and synthesis of diverse probes on a su Lithographic mask design and synthesis of diverse probes on a su

1998-04-13

2000-11-28

MacMillan, Keith D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

530335, 530334, 530333, C07H 2100

Patent

active

061537438

ABSTRACT:
Systems and methods of synthesizing probes on a substrate are provided. One or more shift reticles are utilized to uniformly add monomers to the substrate at specified locations. The shift reticles are shifted relative to the substrate between monomer addition steps. Additionally, characteristics of the desired probes may be specified at synthesis time.

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Fodor et al., "Light-Directed, Spatially Addressable Parallel Chemical Synthesis," Feb. 15, 1991, Research Article.
Brown et al., "An Inexpensive MSI/LSI Mask Making System," IEEE Symposium Proceedings 1981, University Government Industry Microelectronics, Sponsored by IEEE, Starkville, Mississippi, pp. III-31 to III-38.
Southern, E. M., "Analyzing and Comparing Nucleic Acid Sequences by Hybridization to Arrays of Oligonucleotides: Evaluation Using Experimental Models," Genomics, 13, 1992, pp. 1008-1017.
Ed M. Southern, "DNA Chips: Analysing Sequence by Hybridization to Oligonucleotides on a Large Scale," TIG, Mar. 1996, vol. 12, No. 3, pp. 110-115.

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