Lithium detection in liquid biological samples and reagents...

Chemistry: analytical and immunological testing – Metal or metal containing – Li – na – k – rb – cs – fr – be – mg – ca – sr – ba – ra

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C422S067000, C436S073000, C436S164000, C436S166000, C436S172000

Reexamination Certificate

active

10296592

ABSTRACT:
A method of detecting soluble lithium in a liquid biological sample comprising combining: (a) an amount of the biological sample; (b) 2,3,7,8,12,13,17,18-octobromo-5,10,15,20-tetrakis(4-sulphonatophenyl) porphyrin; (c) alkali; (d) detergent; (e) chelating agent; and (f) optionally a suitable solvent; to produce a test sample; detecting absorbance change of the test sample relative to a lithium deficient standard sample at a wavelength of between about 475 nm and about 485 nm, between about 515 nm and about 525 nm or simultaneously between about 475 nm and about 485 nm and between about 515 nm and about 525 nm, wherein absorbance change indicates presence of soluble lithium in the biological sample. Also disclosed is a method of quantitatively measuring soluble lithium ions in a biological sample and a reagent for use in such methods.

REFERENCES:
patent: 4599316 (1986-07-01), Hahn et al.
patent: 4859606 (1989-08-01), Cram et al.
patent: 5055388 (1991-10-01), Vogt et al.
patent: 5110742 (1992-05-01), Shu et al.
patent: 5187103 (1993-02-01), Czech et al.
patent: 5300439 (1994-04-01), Charlton
patent: 5340714 (1994-08-01), Katsilometes
patent: 5344782 (1994-09-01), Lin et al.
patent: 0 579 331 (1994-01-01), None
patent: WO 96/02839 (1996-02-01), None
Semichaevskii, V. D. Chemical Abstracts 1975, 82, abstract 167620g.
Hinoue, T. et al, Chemistry Letters 1997, 763-764.
Gandini, S. C. M. et al, Langmuir 1999, 15, 6233-6243.
Li, Xi-you et al, Macromolecules 2000, 33, 2119-2123.
Semichaevskii, V. D., Fiziologiya i Biokhimiya Kul'turnykh Rastenii 1975, 7, 18-24.
Jacox, R. F., Journal of Clinical Investigation 1953, 32, 661-673.
Jirgensons, B. et al, Makromolekulare Chemie 1963, 60, 25-44.
Canioni, P. et al, Lipids 1980, 15, 6-9.
Gonzalez-Vergara, E. et al, Biochemistry 1985, 24, 6561-6567.
Kano, K. et al, Bulletin of the Chemical Society of Japan 1987, 60, 1281-1287.
Venkatesh, B. et al, Biochemical and Biophysical Research Communications 1996, 223, 390-396.
Richards, R.A., et al., “Observation of a Stable Water-Soluble Lithium Porphyrin,”Inorg. Chem. 35:1940-1944, American Chemical Society (1996).
Sun, H., and Tabata, M., “Separation and transport of lithium of 10-5M in the presence of sodium chloride higher than 0.1 M by 2,3,7,8,12,13,17,18-octabromo-5,10,15,20-tetrakis (4-sulfonatophenyl)porphyrin,”Talanta 49:603-610, Elsevier Science B.V. (Jul. 1999).
Tabata, M., et al., “Metalation of Water-Soluble Octabromoporphyrin with Lithium(I), Cadmium(II), and Mercury(II),”Bull. Chem. Soc. Jpn. 69:673-677, Nippon Kagakukai (1996).
Tabata, M., et al., “Trace of Analysis of Lithium with a Water-Soluble Porphyrin,”J. Inclusion Phenomena and Mol. Recognit. in Chem. 32:267-281, Kluwer Academic Publishers (1998).
Tabata, M., et al., “Spectrophotometric determination of lithium ion using a water-soluble octabromoporphyrin in aqueous solution,”Talenta 46:703-709, Elsevier Science B.V. (1998).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Lithium detection in liquid biological samples and reagents... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lithium detection in liquid biological samples and reagents..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lithium detection in liquid biological samples and reagents... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3744748

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.