Organic compounds -- part of the class 532-570 series – Organic compounds – Rare earth containing
Reexamination Certificate
2005-05-17
2005-05-17
Coleman, Brenda (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Rare earth containing
C540S474000
Reexamination Certificate
active
06894151
ABSTRACT:
The invention relates to crystalline lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane, their production and the recovery of the salt-free gadolinium complex of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10 tetraazacyclododecane from the latter without the use of ion exchangers.
REFERENCES:
patent: 5980864 (1999-11-01), Platzek et al.
patent: 5994536 (1999-11-01), Petrov et al.
patent: 0 448 191 (1991-09-01), None
patent: WO 98 55467 (1998-12-01), None
J. Platzek et al., “Synthesis and Structure of a New Macrocyclic Polyhydroxylated Gadolinium Chelate Used As Contrast Agent for Magnetic Resonance Imaging,” Inorg. Chem., Bd. 36, Nr. 26, 1997, pp. 6086-6093, XP002199426.
Blaszkiewicz Peter
Hoffmann Holger
Petrov Orlin
Platzek Johannes
Coleman Brenda
Millen White Zelano & Branigan
Shering Aktiengesellschaft
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