Liquid vitamin formulations containing vitamin D esters

Details Liquid vitamin formulations containing vitamin D esters Liquid vitamin formulations containing vitamin D esters

1993-07-02

1995-12-26

Kestler, Kimberly J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

514168, C07C40100

Patent

active

054788161

ABSTRACT:
Liquid vitamin formulation containing an ester of antirachitic vitamin D esterified at the 3 carbon position such as vitamin D.sub.3 palmitate, greater than 252 mg/ml water and at least about 100 mg/ml polyhydroxylated solvent such as glycerine. The formulations have improved taste and improved storage stability.

REFERENCES:
patent: 2758923 (1956-08-01), Wakely
D. R. Fraser and E. Kodicek, "Enzyme Studies on the Esterification of Vitamin D in Rat Tissues," Biochem. J., 109, 457-467, 1968.
W. Huber and D. W. Barlow, "Chemical and Biological Stability of Crystalline Vitamins D.sub.2 and D.sub.3 and Their Derivatives," J. Biol. Chem., 149, 125-137, 1943.
Matthew G. Silva, et al., "Reversed-Phase Liquid Chromatographic Determination of Vitamin D in Infant Formulas and Enteral Nutritionals," Journal of AOAC International, 75(3), 566-571, 1992.
Miloslav Rechcigl, Jr., Editor, Handbook of Nutritive Value of Process Food, vol. 1, "Food For Use," CRC Series in Nutrition and Food, 1982.

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