Liquid suspensions of nitrofurantoin

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

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514387, A61K 31415, A61K 910

Patent

active

051788802

ABSTRACT:
Compositions, for the administration of nitrofurantoin to a human or other animal subject, comprising:

REFERENCES:
patent: 2610181 (1952-09-01), Hayes
patent: 3401221 (1968-09-01), Borgmann et al.
patent: 4122157 (1978-10-01), Huber
patent: 4191772 (1980-03-01), Woog et al.
patent: 4370313 (1983-10-01), Davies
The Merck Index, 11th Ed. (Rahway, N.J. Merck & Co., 1989) p. 9010 No. 9011.
H. Seager, "The effect of methylcellulose on the absorption of nitrofurantoin from the gastrointestinal tract," 20 J. Pharm. Pharmacol. 968 (1968).
I. McGilveray et al., "A study of bioavailabilities and dissolution rates of commercial tablets of nitrofurantoin," 23 J. Pharm. Pharmacol. 246S (1971).
M. Soci et al., "Influence of Viscosity on Absorption from Nitrofurantoin Suspensions," 69 J. Pharmaceutical Sciences 403 (1980).
"Nitrofurantoin", Martindale--The Extra Pharmacopoeia, 28th ed. 1049 (1982).
H. Paul et al., "Laboratory Studies with Nitrofurantoin", 56 J. Pharmaceutical Sciences 882 (1967).
N. Shah et al., "Effect of Polymers on Dissolution from Drug Suspensions", 65 J. Pharmaceutical Sciences 1618 (1976).
A. S. Geneidi et al., "Solid Dispersions of Nitrofurantoin, Ethotoin, and Coumarin with Polyethylene Glycol 6000 and Their Coprecipitates with Povidone 25,000", 67 J. Pharmaceutical Sciences 114 (1976).
M. A. El Egakey, "In vitro and in vivo Release Studies of Nitrofurantoin from Coated Crystals", 28 Acta Pharm. Technol. 267 (1982).

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