Liquid-sample-separation laboratory device and method particular

Chemistry: analytical and immunological testing – Including sample preparation – Liberation or purification of sample or separation of...

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422 72, 422101, 422102, 436178, G01N 118

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active

058888314

ABSTRACT:
In a plastic "miniprep" device for separating liquid samples including (i) a first, sample, cylindrical container having an inlet and an outlet opening between which a separation layer is arranged, the outlet opening typically being connected to and enclosed by an outlet spout, fitting within a cylindrical bore of (ii) a second, collecting, container receiving the separated liquid discharged from the outlet spout, the cylindrical first container is (a) of lesser diameter than is the bore, and (b) possessed of longitudinal exterior rib hat hold it eccentric within the bore. According to the (a) lessor diameter and (b) eccentric mounting, access may be had by hypodermic syringe or thin pipette down the side of the first container to separated liquid present at the bottom of the second container. Normally a large number of arrayed sample containers each positioned within a collection container are (i) loaded with samples, typically by use of a pipette, and then (ii) centrifuged in parallel while held in a rack, the (iii) separated liquid being withdrawn by syringe or pipette without necessity of separating the sample and collection containers, and (iv) the used containers discarded.

REFERENCES:
patent: 4871674 (1989-10-01), Matsui et al.
patent: 4953741 (1990-09-01), Jessop et al.
patent: 4956148 (1990-09-01), Grandone
patent: 4956298 (1990-09-01), Diekmann
patent: 5352413 (1994-10-01), Kratzer et al.

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