Optics: measuring and testing – Sample – specimen – or standard holder or support – Fluid containers
Patent
1997-02-14
1998-09-29
Font, Frank G.
Optics: measuring and testing
Sample, specimen, or standard holder or support
Fluid containers
250576, G01N 2105
Patent
active
058152580
ABSTRACT:
A liquid sample cell used in an optical measurement apparatus in which a liquid sample flows through a flow path of the sample cell while a measurement light travels through the liquid sample in the flow path. The liquid sample cell is composed of: a first glass plate and a second glass plate fixed to each other; a groove for constituting the flow path formed in the first glass plate by a photolithographic method; reflection layers formed on the internal surface of the groove and on the internal surface of the other glass plate; and an entrance window and an exit window formed in the reflection layers to let the measurement light into the flow path and to let the measurement light out from the flow path. The measurement light is reflected by the reflection layers many times in the flow path. Since the measurement light travels a long distance in the liquid sample, the sensitivity of the optical measurement is improved, while the capacity of the flow path is minimized preventing diffusion or mixture of components separated by a chromatographic column, for example.
REFERENCES:
patent: 4823168 (1989-04-01), Kamahori et al.
patent: 5273633 (1993-12-01), Wang
patent: 5608517 (1997-03-01), Munk
E. Verpoorte et al.; Sensors and Actuators B, "A silicon flow cell for optical detection in miniaturized total chemical analysis systems", vol. B6, No. 1-3, pp. 66-70, (1992).
DeGrandpe, M.D. et al.; Analytical Chemistry, "Thin Film Planar Waveguide Sensor for Liquid Phase Absorbance Measurements", vol. 62, No. 18, pp. 2012-2017, (1990).
Tsunoda, Kin-Ichi et al.; Applied Spectroscopy, "The Possibility of Signal Enhancement in Liquid Absorption Spectrometry With A Long Capillary Cell Utilizing Successive Total Reflection At The Outer Cell Surface", vol. 43, No. 1, pp. 49-55, (1989).
H. Swerdlow et al., "Three DNA Sequencing Methods Using Capillary Gel Electrophoresis and Laser-Induced Fluorescence", Anal. Chem., 1991, 63, 2835-2841.
Font Frank G.
Merlino Amanda
Shimadzu Corporation
LandOfFree
Liquid sample cell for an optical measurement apparatus does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Liquid sample cell for an optical measurement apparatus, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liquid sample cell for an optical measurement apparatus will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-691006