Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine a

Details Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine a Liquid phase preparation of 2-chloro-5-trifluoromethylpyridine a

1980-09-25

1981-08-18

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21326

Patent

active

042847834

ABSTRACT:
2-chloro-5-trifluoromethylpyridine or a 2-chloro-5-perchlorofluoromethylpyridine is prepared by chlorination of 3-trifluoromethylpyridine or a 3-perchlorofluoromethylpyridine respectively in the liquid phase in the presence of ultra-violet radiation and/or in the presence of a free-radical initiator.

REFERENCES:
patent: 4045499 (1977-08-01), Klein et al.
Fieser & Fieser, Reagents for Organic Synthesis, vol. 6, Wiley Interscience Pub., p. 72, (1977).
Barton et al., Comprehensive Organic Chemistry, vol. I, p. 459, Pergamon Press (1978).

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