Liquid interferon-β formulations

Drug – bio-affecting and body treating compositions – Lymphokine – Interferon

Reexamination Certificate

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Details

C514S002600, C514S004300, C514S008100, C530S351000

Reexamination Certificate

active

06923956

ABSTRACT:
The present invention relates to liquid formulations of human interferon-β. The formulations are characterized in that they have a buffer with a pH in the weakly acidic to neutral range of between 5 and 8, preferably between over 5.5 and 8, and that they exhibit high stability of the interferon-β in solution while retaining the molecular integrity.

REFERENCES:
patent: 5151265 (1992-09-01), Hwang-Felgner et al.
patent: 5358708 (1994-10-01), Patel
patent: 0 284 249 (1988-09-01), None
patent: 0 374 257 (1990-06-01), None
patent: 0 529 300 (1993-03-01), None
patent: WO89/02750 (1989-04-01), None
patent: WO92/15614 (1992-09-01), None
patent: 98 28007 (1998-07-01), None
Abstract/Figure, EMBL Research Reports, Table of Contents (1 page) 2001.
“Opposition of Bioceuticals Arzneimittel AG” to EP APN 98950074.9: Jul. 4, 2003; Jul. 31, 2003.
“Opposition of Intellectual Property Services” to EP APN 98950074.9: Jul. 4, 2003; Jul. 10, 2003.

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