Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Hormone or other secreted growth regulatory factor,...
Reexamination Certificate
2005-03-30
2010-02-16
Spector, Lorraine (Department: 1647)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Hormone or other secreted growth regulatory factor,...
C514S012200, C514S002600, C530S399000
Reexamination Certificate
active
07662393
ABSTRACT:
The invention relates to a liquid formulation comprising a growth hormone or a substance, which stimulates release or potentiates the activity of endogenous hGH; a polyethylene-polypropylene glycol; a citrate/phosphate buffer, an alkali metal salt and an alkaline earth metal salt or a pseudo alkaline earth metal salt, and to a process of preparation thereof.
REFERENCES:
patent: 4637834 (1987-01-01), Thurow
patent: 5017609 (1991-05-01), Escobar et al.
patent: 5461030 (1995-10-01), Lindenbaum
patent: 5567677 (1996-10-01), Castensson et al.
patent: 5597802 (1997-01-01), Clark et al.
patent: 6759393 (2004-07-01), Morsey et al.
patent: 2003/0190291 (2003-10-01), Stevenson et al.
patent: 2006/0252682 (2006-11-01), Donati et al.
patent: 0131864 (1984-07-01), None
patent: 0211601 (1986-07-01), None
patent: 9319776 (1993-10-01), None
patent: 9403198 (1994-02-01), None
patent: 9729767 (1997-08-01), None
patent: WO/97/39768 (1997-10-01), None
patent: WO/01/03741 (2001-01-01), None
patent: WO/2004/004780 (2004-01-01), None
Altschul, S.F. et al., “Basic Local Alignment Search Tool”, J. Mol. Biol., 215:403-410 (1990).
Altschul, S.F. et al., “Gapped BLAST and PSI-BLAST: A New Generation of Protein Database Search Programs”, Nucleic Acids Research, 23:3389-1402 (1997).
Becker, G.W. et al., “Isolation and Characterization of a Sulfoxide and a Desamido Derivative of Biosynthetic Human Growth Hormone”, Biotechnology and Applied Biochemistry, 10:326-327 (1988).
Bewley, T.A. et al., “Sequence Comparison of human Pituitary Growth Hormone, Human Chorionic Somatomammotropin, and Ovine Pituitary Growth and Lactogenic Hormones”, Int. J. Peptide Res., 4:281-287 (1972).
Chen, E.Y. et al., “The Human Growth Hormone Locus: Nucleotide Sequence, Biology, and Evolution”, Genomics, 4:479-497 (1989).
Devereux, J. et al., “A Comprehensive Set of Sequence Analysis Programs for the VAX”, Nucleic Acids Research, 12:387-395 (1984).
Gertler, A. et al., “Inhibition of Lactogenic Activities of Ovine Prolactin and Human Growth Hormone (hGH) by a novel Form of a Modified Recombinant hGH”, Endocrinology, 118:720-726 (1986).
Goeddel, S. V. et al., “Direct Expression inEscherichia coliof a DNA Sequence Coding for Human Growth Hormone”, Nature, 281:544-548 (1979).
Graf, L. et al., “Human Somatotropin Selective Removal with Trypsin of Residues 135-145 from the Hormone Molecule with no Loss of Biological Activities”, The Journal of Biological Chemistry, 257:2365-2369 (1982).
Grantham, R., “Amino Acid Difference Formula to Help Explain Protein Evolution”, Science, 185:862-864 (1974).
Hsiung, H. M. et al., “Use of Bacteriocin Release Protein inE. colifor Excretion of Human Growth Hormone into the Culture Medium”, Biotechnology, 7:267-271.
Jorgensen, K.D. et al., “Pharmacokinetics of Biosynthetic and Pituitary Human Growth Hormones in Rats”, Pharmacology & Toxicology, 63:129-134 (1988).
Kramer, M. S. et al., “Distinct Mechanism for Antidepressant Activity by Blockade of Central Substance P Receptors”, Science, 281:1640-1645 (1998).
Lewis, U.J. et al., “Enhancement of the Hyperglycemic Activity of human Growth Hormone by Enzymic Modification”, Endocrinology, 101:1587-1603 (1977).
Lewis, U.J. et al., “Human Growth Hormone: Additional Members of the Complex”, Endocrinology, 104:1256-1265 (1979).
Lewis, U.J. et al., “The 20,000-Dalton Variant of Human Growth Hormone: Location of the Amino Acid Deletions”, Biochemical and Biophysical Research Communications, 92:511-516 (1980).
Lewis, U.J. et al., “Altered Proteolytic Cleavage of Human Growth Hormone as a Result of Deamidation”, The Journal of Biological Chemistry, 256-:11645-11650 (1981).
Martial, J. A. et al., “Human Growth Hormone: Complementary DNA Cloning and Expression n Bacteria”, Science, 205:602-607 (1979).
Meinkoth, J. et al., “Hybridization of Nucleic Acids Immobilized on Solid Supports”, Analytical Biochmistry, 138:267-284 (1984).
Moore, J.A. et al., “Equivalent Potency and Pharmacokinetics of Recombinant Human Growth Hormones with or without an N-Terminal Methionine”, Endocrinology, 122:2920-2926 (1988).
Pearson, W. R. et al., “Improved Tools for Biological Sequence Comparison”, Proc. Natl. Acad. Sci. USA, 85:2444-2448 (1988).
Pearson, W. R., “Rapid and Sensitive Sequence Comparison with FASTP and FASTA”, Methods in Enzymology, 183:63-98 (1990).
Singh, R. N. P. et al., “Modified Forms of Human Growth Hormone with Increased Biological Activities”, Endocrinology, 94:883-891 (1974).
Smith, T.F. et al., “Identification of Common Molecular Subsequences”, J. Mol. Biol., 147:195-197 (1981).
Thorlacius-Ussing, O. “Zinc in the Anterior Pituitary of Rat: A Histochemical and Analytical Work”, Neuroendocrinology, 45:233-242 (1987).
Lewis et al., “A Naturally Occurring Structural Variant of Human Growth Hormone”, The Journal of Biological Chemistry, 253:2679-2687 (1978).
Arvinte Tudor
Luet Kleiber Karnine
Ares Trading S.A.
Browdy and Neimark PLLC
Spector Lorraine
Stoica Elly-Gerald
LandOfFree
Liquid growth hormone formulation and method of use does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Liquid growth hormone formulation and method of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liquid growth hormone formulation and method of use will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4155392