Chemistry: electrical and wave energy – Apparatus – Electrophoretic or electro-osmotic apparatus
Patent
1995-11-09
1998-12-08
Bell, Bruce F.
Chemistry: electrical and wave energy
Apparatus
Electrophoretic or electro-osmotic apparatus
209451, 209454, 422 82, 422103, 422134, 417 50, 141 31, G01N 2726, G01N 2100, B01L 1100
Patent
active
058463968
ABSTRACT:
The present invention provides a liquid distribution system, which is useful in a number of contexts, including in accomplishing various synthetic, diagnostic and drug screening reactions. The distribution system can comprise an alpha reservoir and a beta reservoir, a first set of parallel and adjacent first and second feeder channels and a second set of parallel and adjacent third and fourth feeder channels which are offset from the first and second feeder channels, wherein (a) the first and third feeder channels are connected to the alpha reservoir via a first connector channel that is situated above or below the second and fourth feeder channels and are independent of the beta reservoir and (b) the second and fourth feeder channels are connected to the beta reservoir via a second connector channel that is situated above or below the first and third feeder channels and are independent of the alpha reservoir. The distribution system is preferably a microscale distribution system. Various particular mechanisms for controlling flow into a liquid distribution system are described.
REFERENCES:
patent: 3494723 (1970-02-01), Gray
patent: 3615241 (1971-10-01), Low et al.
patent: 3957583 (1976-05-01), Gibson et al.
patent: 4038151 (1977-07-01), Fadler et al.
patent: 4272119 (1981-06-01), Columbus
patent: 4276048 (1981-06-01), Leaback
patent: 4283262 (1981-08-01), Cormier et al.
patent: 4310399 (1982-01-01), Columbus
patent: 4385115 (1983-05-01), de Zabala et al.
patent: 4412785 (1983-11-01), Roman
patent: 4426451 (1984-01-01), Columbus
patent: 4495025 (1985-01-01), Haskell
patent: 4533430 (1985-08-01), Bower
patent: 4589952 (1986-05-01), Behringer et al.
patent: 4601881 (1986-07-01), Webster
patent: 4676274 (1987-06-01), Brown
patent: 4683914 (1987-08-01), Brisland
patent: 4753775 (1988-06-01), Ebersole et al.
patent: 4756884 (1988-07-01), Hillman et al.
patent: 4891120 (1990-01-01), Sethi et al.
patent: 4908112 (1990-03-01), Pace
patent: 4948961 (1990-08-01), Hillman et al.
patent: 4960486 (1990-10-01), Perkins et al.
patent: 4963498 (1990-10-01), Hillman et al.
patent: 4999283 (1991-03-01), Zavos et al.
patent: 4999284 (1991-03-01), Ward et al.
patent: 4999286 (1991-03-01), Gawel et al.
patent: 5000817 (1991-03-01), Aine
patent: 5001048 (1991-03-01), Taylor et al.
patent: 5003822 (1991-04-01), Joshi
patent: 5006749 (1991-04-01), White
patent: 5063081 (1991-11-01), Cozzette et al.
patent: 5066938 (1991-11-01), Kobashi et al.
patent: 5073029 (1991-12-01), Eberly et al.
patent: 5077017 (1991-12-01), Gorin et al.
patent: 5104813 (1992-04-01), Besemer et al.
patent: 5112455 (1992-05-01), Cozzette et al.
patent: 5118384 (1992-06-01), Harmone et al.
patent: 5129261 (1992-07-01), Riley
patent: 5129262 (1992-07-01), White et al.
patent: 5140161 (1992-08-01), Hillman et al.
patent: 5141868 (1992-08-01), Shanks et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5144139 (1992-09-01), Hillman et al.
patent: 5147607 (1992-09-01), Mochida
patent: 5156810 (1992-10-01), Ribi
patent: 5164598 (1992-11-01), Hillman et al.
patent: 5176203 (1993-01-01), Larzul
patent: 5180288 (1993-01-01), Richter et al.
patent: 5186001 (1993-02-01), Muntz
patent: 5188963 (1993-02-01), Stapleton
patent: 5189914 (1993-03-01), White et al.
patent: 5194133 (1993-03-01), Clark et al.
patent: 5200051 (1993-04-01), Cozzette et al.
patent: 5204525 (1993-04-01), Hillman et al.
patent: 5212988 (1993-05-01), White et al.
patent: 5220189 (1993-06-01), Higashi et al.
patent: 5229297 (1993-07-01), Schnipelsky et al.
patent: 5230864 (1993-07-01), Columbus
patent: 5238853 (1993-08-01), Calzi et al.
patent: 5241363 (1993-08-01), Garner
patent: 5250263 (1993-10-01), Manz
patent: 5252743 (1993-10-01), Barrett et al.
patent: 5262127 (1993-11-01), Wise et al.
patent: 5270170 (1993-12-01), Schatz et al.
patent: 5277754 (1994-01-01), Hadimioglu et al.
patent: 5279791 (1994-01-01), Aldrich et al.
patent: 5288463 (1994-02-01), Chemelli
patent: 5296114 (1994-03-01), Manz
patent: 5296375 (1994-03-01), Kricka et al.
patent: 5304487 (1994-04-01), Wilding et al.
patent: 5312590 (1994-05-01), Gunasingham
patent: 5324483 (1994-06-01), Cody et al.
patent: 5324633 (1994-06-01), Foder et al.
patent: 5359115 (1994-10-01), Campbell et al.
patent: 5384261 (1995-01-01), Winkler et al.
patent: 5412087 (1995-05-01), McGall et al.
patent: 5420328 (1995-05-01), Campbell
patent: 5424186 (1995-06-01), Fodor et al.
patent: 5427946 (1995-06-01), Kricka et al.
patent: 5463564 (1995-10-01), Agrafiotis et al.
patent: 5480614 (1996-01-01), Kamahori
patent: 5580523 (1996-12-01), BArd
Andreas Manz et al., Trends in Analytical Chemistry, 10(5):144-148 (1991).
Database Search * on micropumps.
Search Report for WO 93/22421, Nov. 11, 1993.
Search Report for WO 93/22055, Nov. 11, 1993.
Search Report for WO 93/22054, Nov. 11, 1993.
Search Report for WO 93/22053, Nov. 11, 1993.
Gazette entry for Tsui et al., Variable Range Position Indicator, U.S. Patent No. 5,345,215, Jun. 17, 1993.
Gazette entry for Murphy et al., Automated Capillary Scanning System, U.S. Patent No. 5,009,003, Feb. 14, 1990.
Woolley et al., Ultra-High Speed DNA Fragment Separations Using Microfabricated Capillary Array Electrophoresis Chips, Proc. Natl. Acad. Sci. USA 91:11348-11352, Nov. 1994.
Dasgupta et al., Electroosmosis: A Reliable Fluid Propulsion System for Flow Injection Analysis, Anal. Chem. 66:1792-1798, 1994 no month available.
Harmon et al., Selectivity in Electrophoretically Mediated Microanalysis by Control of Product Detection Time, Anal. Chem. 66:3797-3805, 1994 no month available.
Patterson, et al., Electrophoreically Mediated Microanalysis of Calcium, Journal of Chromatography A, 662:389-395, 1994.
Microfabricated Device is Chemistry Lab on a Chip, Chemical & Engineering News, Dec., 1991.
Harmon et al., Mathematical Treatment of Electrophoretically Mediated Microanalysis, Anal. Chem. 65:2655-2662, 1993 no month availble.
Avila and Whitesides, Catalytic Activity of Native Enzymes During Capillary Electrophoresis: An Enzymatic Microreactor, J. Org. Chem. 58:5508-5512, 1993 no month availble.
Harmon, et al., Electrophoretically Mediated Microanalysis of Ethanol, J. Chormatog. A, 657:429-434, 1993 no month avaible.
Bao and Regnier, Ultramicro Enzyme Assays in a Capillary Electrophoretic System, J. Chrom. 608:217-224, 1992 no month available.
Richeter et al., A Micromachined Electrohydynamic (EHD0 Pump, Sensors and Actuators A, 29:159-168, 1992 no month available.
Bart et al., Microfabricated Electrohydrodynamic Pumps, Sensors and Actuators, A21-A23:193-197, 1990 no month available.
Melcher, Traveling-Wave Induced Electroconvection, The Physics of Fluids, 9:1548-1555, 1966 no month available.
Pickard, Ion Drag Pumping, I. Theory, J. Applied Physics 34:246-250, 1963.
Pickard, Ion Drag Pumping. II. Experiment, J. Applied Physics, 34:251-258, 1963 no month available.
Stuetzer, Ion Drag Pumps, J. Applied Physics, 31:136-146, 1960 no month available.
Tracey, et al., Microfabricated Microhaemorheometer, pp. 82-84, 1991 no month available.
Medynski, Synthetic peptide Combinatorial Libraries, Bio/Technology, vol. 12, Jul. 1994.
Jacobson et al., Precolumn Reations with Electrophoretic Analysis Integrated on a Microchip, Anal, Chem., 66:4127-4132 no month available.
Jacobson, et al., Effects of Injection Schemes and Column Geometry on the Performance of Microchip Electrophoresis Devices, Anal. Chem. 1994, 66:1107-1113 no month available.
Jacobson, et al., High-Speed Separations on a Microchip, anal. Chem. 1994, 66:1114-1118 no month available.
Fan, et al., Micromachining of Capillary Electrophoresis Injectors and Separators on Glass Chips and Evaluation of Flow at Capillary Intersections, Anal. Chem., 1994, 6:177-184 no month available.
Megregany, Microeletromechanical Systems, Circuits and Devices, Jul. 1993.
Harrison, et al., Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip, Science, vol. 261, Aug. 13, 1993.
Harrison, et al., Capillary Electrophoresis and Sample Injection Systems Integrated on a Planar Glass Chip, Anal. Chem. 1992, 64:1926-1932 n
Braun Paul Leonard
Cherukuri Satyam Choudary
Chiang William
Demers Robert R.
Fan Zhonghui Hugh
Bell Bruce F.
Burke William J.
Noguerola Alex
Sarnoff Corporation
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