Chemistry: analytical and immunological testing – Including sample preparation – Volumetric liquid transfer
Reexamination Certificate
2005-09-13
2005-09-13
Warden, Jill (Department: 1743)
Chemistry: analytical and immunological testing
Including sample preparation
Volumetric liquid transfer
C436S174000, C436S177000, C436S179000, C422S091000, C422S105000, C422S105000
Reexamination Certificate
active
06943035
ABSTRACT:
A multiwell plate for microarraying comprising a self-sealing lower membrane and optionally also a self-sealing upper membrane. Spotting is performed by pushing a pin down through the liquid and then on to pierce the self-sealing lower membrane. A slide having an upper spotting surface is arranged under the well plate. The liquid sample forced through the lower membrane by the pin tip can thus be deposited directly onto the spotting surface. The pin is then withdrawn upwards through the lower membrane, which automatically reseals preventing further loss of liquid. The optional resealable upper membrane also prevents loss of sample liquid by evaporation and spillage. By contrast to the prior art, there is the major advantage that the pin head does not have to traverse between the well plate and slide to collect sample liquid, thus dramatically increasing operational speed for an automated microarraying apparatus employing the multiwell plate. Excellent spot reproducibility is also observed.
REFERENCES:
patent: 3894950 (1975-07-01), Ayres et al.
patent: 4827780 (1989-05-01), Sarrine et al.
patent: 5281540 (1994-01-01), Merkh et al.
patent: 5578495 (1996-11-01), Wilks
patent: 5789251 (1998-08-01), Astle
patent: 5916812 (1999-06-01), Chen et al.
patent: 5935523 (1999-08-01), McCandless et al.
patent: 5951783 (1999-09-01), Kontorovich et al.
patent: 5972694 (1999-10-01), Mathus
patent: 6030582 (2000-02-01), Levy
patent: 6045755 (2000-04-01), Lebl et al.
patent: 6054099 (2000-04-01), Levy
patent: 6254833 (2001-07-01), Shumate et al.
patent: 6361744 (2002-03-01), Levy
patent: 6534019 (2003-03-01), Inoue
patent: 6551557 (2003-04-01), Rose et al.
patent: 98/36260 (1998-08-01), None
patent: 00/01798 (2000-01-01), None
Davies Douglas
Haslam James Keith
Stephens Sarah Katharine
Foley & Lardner LLP
Genetix Limited
Handy Dwayne K
Warden Jill
LandOfFree
Liquid dispensing apparatus and method does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Liquid dispensing apparatus and method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liquid dispensing apparatus and method will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3451267