Liquid detergent with stabilized enzyme

Compositions – Water-softening or purifying or scale-inhibiting agents

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252DIG12, 252DIG2, 435264, 435184, 435188, C11D 3386, C11D 3384

Patent

active

051787890

ABSTRACT:
Liquid detergent containing enzymes particularly proteases are stabilized against enzyme degradation prior to use by inclusion of an inhibitor of the enzyme which binds to the enzyme such that prior to use of the detergent at least about 90% of the enzyme is bound to the enzyme inhibitor essentially at the enzyme active site. Such enzyme inhibitor so selected can be used effectively in concentrations much lower than previously taught.

REFERENCES:
patent: 4169817 (1979-02-01), Weber
patent: 4261868 (1981-04-01), Hora et al.
patent: 4318818 (1982-09-01), Letton
patent: 4959179 (1990-09-01), Aronson et al.
patent: 5037292 (1991-12-01), Hessell et al.
patent: 5039446 (1991-08-01), Estell et al.
Empie et al. "Thermodynamics and Kinetics of Single Residue Replacement in Avian Ovomucoid Third Domain: Effect on Inhibitor Interactions with Serine Proteinases" vol. 21, No. 2 1982 pp. 2274-2284.
Park et al., "Covalent Hybrids of Ovomucoid Third Domain Made From One Synthetic and One Natural Pestide Bond" vol. 144, No. 1, 499-504.

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