Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-06-07
1998-06-02
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
420445, 420450, 420484, 420486, 420488, 420489, 6048911, A61K 900, A61K 9127, A61F 1300
Patent
active
057595631
ABSTRACT:
Improved biocompatible liquid delivery compositions, which are useful for the formation of sustained release delivery systems for active agents, are provided. The compositions include liquid formulations of a biocompatible polymer or prepolymer in combination with a controlled release component. The controlled release component includes an active agent. These compositions may be introduced into the body of a subject in liquid form which then solidify or cure in situ to form a controlled release implant or a film dressing. The liquid delivery compositions may also be employed ex situ to produce a controlled release implant. Methods of forming a controlled release implant and employing the liquid formulations in the treatment of a subject are also provided.
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Brouwer Gerbrand
Dunn Richard L.
Krinick Nancy L.
Radomsky Michael L.
Tipton Arthur J.
Atrix Laboratories, Inc.
Kishore Gollamudi S.
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