Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-11-30
2010-06-08
Bertoglio, Valarie (Department: 1632)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007200, C435S325000, C435S394000, C436S501000
Reexamination Certificate
active
07732152
ABSTRACT:
The present invention is directed to liquid crystalline substrates useful in the culture of cells and methods of their use. In certain embodiments, the invention provides methods and devices for imaging changes (e.g., reorganization) of extracellular matrix components by living cells.
REFERENCES:
patent: 2005/010160 (2005-02-01), None
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Geiger, B et al, 2001, Nature Reviews: 2:793-805.
Balaban et al, 2001, Nature cell Biology, 3:466-472.
ISR, PCT/US2006/061414, mailed Oct. 15, 2007, Wisconsin Alumni Research Foundation.
Yan-Yeung Luk et al., Non-Toxic Thermotropic Liquid Crystals for use with Mammalian Cells, Liquid Crystals, Taylor and Francis, Abindgon, GB, vol. 31, No. 5, May 2004, p. 611-621.
Li-Lin Cheng et al., Compatibility of Lyotropic Liquid Crystals with Viruses and Mammalian Cells that Support the Replication of Viruses, Biomaterials, Elsevier Science Publishers BV., Barking, GB, vol. 26, No. 34, Jun. 13, 2005, p. 7173-7182.
Laurence Besseau et al., Production of Ordered Collagen Matrices for Three-Dimensional Cell Culture, Biomaterials, Elsevier Science Publishers BV., Barking, GB, vol. 23, No. 1, Jan. 1, 2002, p. 27-36.
Abbott Nicholas L.
De Pablo Juan J.
Huang Elise
Lockwood Nathan A.
Mohr Jeffrey C.
Bertoglio Valarie
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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