Liquid core microdroplets for ultrasound imaging

Surgery – Truss – Pad

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424 95, A61B 800

Patent

active

056069731

ABSTRACT:
Ultrasonic imaging agents comprising an aqueous suspension of negatively buoyant aspherical microdroplets composed of a biocompatible liquid core encapsulated by a shell of amphiphilic biocompatible material are prepared by milling a mixture of a solution of the shell material and vaporized liquid and cooling the milled mixture to below the boiling point of the liquid.

REFERENCES:
patent: 5409688 (1995-04-01), Quay
patent: 5425366 (1995-06-01), Reinhardt et al.
patent: 5439686 (1995-08-01), Desai et al.
patent: 5469854 (1995-11-01), Unger et al.

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