Liquid purification or separation – With means to add treating material – Chromatography
Reexamination Certificate
2000-03-17
2001-11-13
Therkorn, Ernest G. (Department: 1723)
Liquid purification or separation
With means to add treating material
Chromatography
C210S085000, C210S141000, C210S143000, C210S656000, C422S070000
Reexamination Certificate
active
06315901
ABSTRACT:
BACKGROUND OF THE INVENTION AND RELATED ART STATEMENT
The present invention relates to a liquid chromatography which isolates and analyzes various chemical substances by moving the chemical substances with a mobile phase using a column.
A traditional high-speed liquid chromatography sometimes has a function of being able to check a remaining quantity of a mobile phase stored in the instrument on its monitor in order to prevent the interruption of analysis due to insufficient mobile phase during the course of continuous analysis. An operator manually calculates a quantity of the mobile phase required for continuous analysis and decides whether any mobile phase should be added by comparing the required quantity of the mobile phase with the remaining quantity of the mobile phase displayed on the monitor.
The continuous analysis requires a sufficient amount of rinsing fluid or liquid to be used in an auto-sampling unit. If the rinsing fluid supplied to the instrument does not suffice, more rinsing fluid should be added. To check the remaining quantity of the rinsing fluid installed in the instrument, an operator has to look at the rinsing fluid reservoir. This task is troublesome for the operator.
Also, it is necessary to check how much of the drained mobile phase and drained rinsing fluid is filled in the drainage reservoir. Since the operator has to actually look at the drainage reservoir to check the quantity of the waste fluid, it is inconvenient. If checking the quantity of the accumulating waste fluid is forgotten, the drainage reservoir may sometimes overflow.
Further, an operator has to manually calculate how much mobile phase is required for the continuous analysis at the beginning of the continuous analysis. Still further, the operator has to decide whether the remaining quantity of the mobile phase is sufficient for the continuous analysis by comparing the required quantity of the mobile phase with the remaining quantity of the mobile phase. These tasks are troublesome for the operator.
The purpose of this invention is to provide a liquid chromatography for reducing operator's tasks regarding the mobile phase, rinsing fluid, and waste fluid.
SUMMARY OF THE INVENTION
A liquid chromatography of the invention is basically formed of a column for separating a sample, a mobile phase reservoir for storing a mobile phase, a fluid pump connected to the mobile phase reservoir for sending the mobile phase to the column, a sample introducing section situated between the fluid pump and the column for providing the sample into the mobile phase, a rinsing fluid reservoir connected to the sample introducing section and storing a rinsing fluid or liquid for cleaning the sample introducing section by the rinsing fluid, and a drainage reservoir connected to the column and the sample introducing section for storing a used mobile phase and used rinsing fluid as a waste fluid or liquid.
The liquid chromatography of the invention further includes a mobile phase quantity integrator for calculating a quantity of the mobile phase sent by the fluid pump after the waste fluid in the drainage reservoir has been discarded and the drainage reservoir has been emptied, a rinsing fluid quantity integrator for integrating a quantity of the rinsing fluid used in the sample introducing section after the waste fluid in the drainage reservoir has been discarded and the drainage reservoir has been emptied, a waste fluid quantity calculation unit electrically connected to the mobile phase quantity integrator and the rinsing fluid quantity integrator for calculating a quantity of the waste fluid stored in the drainage reservoir based on the quantity of the mobile phase calculated by the mobile phase quantity integrator and the quantity of the rinsing fluid calculated by the rinsing fluid quantity integrator, and a display unit electrically connected to the waste fluid calculation unit for displaying the quantity of the waste fluid calculated by the waste fluid quantity calculation unit.
REFERENCES:
patent: 5350520 (1994-09-01), Kikumoto
patent: 5358639 (1994-10-01), Yasuda
patent: 5407569 (1995-04-01), Greenley
patent: 5443734 (1995-08-01), Fetner
patent: 5457626 (1995-10-01), Wolze
patent: 5531959 (1996-07-01), Johnson
patent: 5670379 (1997-09-01), Ito
patent: 5730867 (1998-03-01), Drew
patent: 5738783 (1998-04-01), Shirota
patent: 5755559 (1998-05-01), Allington
patent: 5827946 (1998-10-01), Klee
patent: 5830353 (1998-11-01), Henderson
patent: 5938931 (1999-08-01), Ono
patent: 6036856 (2000-03-01), Ono
patent: 6221251 (2001-04-01), Ono
Kanesaka & Takeuchi
Shimadzu Corporation
Therkorn Ernest G.
LandOfFree
Liquid chromatography does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Liquid chromatography, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liquid chromatography will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2587004