Liquid chromatography

Liquid purification or separation – Processes – Chromatography

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2101982, B01D 1508

Patent

active

052098532

ABSTRACT:
A method of analysis by liquid chromatography and liquid chromatograph apparatus are disclosed. The method and apparatus are arranged to enable a chromatographer to locate an optimum solvent composition for a particular analysis. A display is produced which shows simltaneously a contour map of chromatogram quality across an isoeluotropic plane and a predicted chromatogram corresponding to a selected point on the isoeluotropic plane.

REFERENCES:
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patent: 4719017 (1988-01-01), Uchino
patent: 4969993 (1990-11-01), Nash
Berridge, "Using a Microprocessor in High Performance Liquid Chromatography", Microprocessors and Microsystems 7(1) Jan. 1983, pp. 19-23.
Haleem Issaq, "Computer-Assisted HPLC", American Laboratory, Feb. 1983, pp. 41-46.
Naisch, "Evaluation of a Complete HPLC Solvent Optimization System Involving Piece-Wise Quadratic Modelling", Chromatographia, vol. 29, No. 1/2, Jan. 1990, pp. 79-89.
Schoenmakers, "Criteria for Judging the Quality of Separation in Chromatograms Containing Solvent Peaks" Chromatographia 24 (1987) pp. 579-587.
Schoenmakers, "Correction of the Resolution Function for Non-Ideal Peaks", Journal of Chromatography 458 (1988) pp. 355-370.
Schoenmakers, "Criteria for Comparing the Quality of Chromatographs with Great Variations in Capacity Factors", Journal of Liquid Chromatography, 10(8 and 9), 1865-1886 (1987).
Vandeginste, "Multicomponent Self-Modelling Curve Resolution in High-Performance Liquid Chromatography by Iterative Target Transformation Analysis", Analytica Chimica Acta, 173 (1985) pp. 253-264.

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