Liquid chromatographic method and post-column effluent treatment

Liquid purification or separation – Processes – Chromatography

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2101982, 422 70, B01D 1508

Patent

active

044513747

ABSTRACT:
Reagent is added to liquid chromatographic effluent to increase detection sensitivity of sample bands, or to enhance sensitivity with respect to interfering bands which overlap sample bands of interest, using one or more hollow fibers immersed within mobile reagent which is permeated through the walls of the fibers and, thus, ultimately diffused into the column effluent.

REFERENCES:
patent: 3463615 (1969-08-01), Sochor
patent: 3472627 (1969-10-01), Hadina
patent: 3751879 (1973-08-01), Allington
patent: 4181853 (1980-01-01), Abu-Shumays
patent: 4233030 (1980-11-01), Twitchett
patent: 4251218 (1981-02-01), Diggens
R. S. Deelder et al., "Post-Column Reactor Systems in Liquid Chromatography", J. of Chrom., 149 (1978) pp. 669-682.
CECl On-Line Column Eluate Concentrator, Bulletin I-118G 6/75, pp. 1-12.
Vance Nau et al., "Application of Microporous Membranes to Chemiluminescence Analysis", Anal. Chem., vol. 51, No. 3, Mar. 1979, pp. 424-428.
Introduction to Modern Liquid Chromatography by Snyder et al., 2nd edition, John Wiley & Sons, New York, pp. 740-746, 1979.

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