Liquid chromatographic method and apparatus for analyzing biolog

Details Liquid chromatographic method and apparatus for analyzing biolog Liquid chromatographic method and apparatus for analyzing biolog

1990-12-11

1994-05-03

Housel, James C.

Chemistry: analytical and immunological testing

Peptide, protein or amino acid

Glycoproteins

436 63, 436111, 436161, 436172, 436175, 436179, G01N 3014, G01N 3388

Patent

active

053087747

ABSTRACT:
Physiologically active substances contained in a biological sample not subjected to deproteinization can be converted to their derivatives at a high efficiency without being adversely affected by the protein present in the sample, and accordingly the analysis of said physiologically active substances in the form of said derivatives can be performed at a high precision.

REFERENCES:
patent: 3934979 (1976-01-01), McClure
patent: 4705757 (1987-11-01), Ohkura
patent: 5011608 (1991-04-01), Damjanovic
"A New HPLC Concept for Directly Analyzing Drugs in Biological Matrices: Shielded Hydrophobic Phases", pp. 2-4, Sep. 1988, 17th International Symposium on Chromatography.
High Performance Liquid Chromatography Handbook, Analytical Chemical Society of Japan, Maruzen Corp., Nov. 1985.

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