Liquid chromatograph-direct coupled mass spectrometer

Details Liquid chromatograph-direct coupled mass spectrometer Liquid chromatograph-direct coupled mass spectrometer

1990-03-12

1993-08-31

Therkorn, Ernest G.

Liquid purification or separation

Processes

Chromatography

2101982, 250288, 422 70, B01D 1508

Patent

active

052406164

ABSTRACT:
A liquid chromatograph-direct coupled mass spectrometer, which comprises a liquid chromatograph section, a mass spectrometer section and an interface section coupling the liquid chromatograph section with the mass spectrometer section, the interface section being provided with a first nebulizing means for nebulizing an eluate of a hydrophobic solvent containing a sample in solution introduced from the liquid chromatograph section through a capillary continuously into a vacuum or atmospheric pressure region and the first nebulizing means being further provided with a second nebulizing means for nebulizing a hydrophilic solvent and with a heating means for heating the first and second nebulizing means has a high separability and has no limit to selection of a mobile phase solvent and an ionization solvent.

REFERENCES:
patent: 4298795 (1981-11-01), Takeuchi
patent: 4570068 (1986-02-01), Sakairi
patent: 4607163 (1986-08-01), Mizuno
patent: 4667100 (1987-05-01), Lagna
patent: 4687929 (1987-08-01), Browner
patent: 4708782 (1987-11-01), Andresen
patent: 4740298 (1988-04-01), Andresen
patent: 4762995 (1988-08-01), Browner
Corey, "Liquid Chromatography/Mass Spectrometry," Anal. Chem., vol. 58. No. 14, pp. 1451A-1461A, Dec. 1986.
Karger, "On-line Reversed Phase Liquid Chromatography--Mass Spectrometry", Anal. Chem. vol. 51, No. 14, pp. 2324-2328, Dec. 1979.
Games, Continuous Flow Fast Bombardment Liquid Chromatography/Mass Spectrometry, Biomedical and Environmental Mass Spectrometry, vol. 15, pp. 179-182 (1988).
Apfell Gas-Nebulized Direct Liquid Introduction Interface for Liquid Chromatography/Mass Spectrometry, Anal. Chem. vol. 55, pp. 2280-2284 Dec. 1983.
Tsuge, "Vacuum Nebulizing Interface for Direct Coupling of Micro-Liquid Chromatograph and Mass Spectrometer Analytical Chemistry", vol. 51, No. 1, Jan. 1979, pp. 166-169.
Hirata, "The Application of a New Sampling Technique" Organic Mass Spectrometry, vol. 14, No. 3, 1979, pp. 126-128.

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