Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1987-02-10
1990-01-30
Evans, J. E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514555, 562621, 562623, 562874, 260545R, C07C 8310, A61K 31185, A61K 31085, A61K 3113
Patent
active
048974226
ABSTRACT:
Compounds of the formula: ##STR1## where R.sub.1 is amino or methyl; R.sub.2 is C.sub.1 -C.sub.2 alkyl; R.sub.3 is one or more substituents selected from hydrogen, halogen or trihalomethyl; R.sub.4 is one or more substituents selected from hydrogen, halogen, trihalomethyl, C.sub.1 to C.sub.4 alkoxy or C.sub.1 to C.sub.4 alkyl; and M is hydrogen, a pharmaceutically acceptable cation, aroyl, or C.sub.1 to C.sub.6 alkoyl are inhibitors of 5- and/or 12-lipoxygenase enzymes.
REFERENCES:
patent: 3855242 (1984-12-01), Chapman et al.
patent: 3890377 (1975-06-01), Marshall
patent: 3928384 (1975-12-01), Descamps et al.
patent: 4604407 (1986-08-01), Haslanger et al.
patent: 4738986 (1988-04-01), Kneen et al.
Abbott Laboratories
Crowley Steven R.
Evans J. E.
Stevenson Robert W.
Weinstock Steven F.
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