Lipoxygenase inhibiting compounds

Details Lipoxygenase inhibiting compounds Lipoxygenase inhibiting compounds

1986-04-09

1988-08-02

Bond, Robert T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

514290, 514298, 514309, 514312, 546 14, 546101, 546108, 546110, 546142, 546155, A61K 31695, C07F 710

Patent

active

047614030

ABSTRACT:
Hydroxy quinol-1-one and quinol-2-one based compounds found to be potent inhibitors of 5-, 12-, and 15-lipoxygenase enzymes.

REFERENCES:
patent: 3455931 (1969-07-01), Leov
patent: 4393075 (1963-07-01), Terao et al.
R. T. Coutts et al., J. Pharm. Sci., 1965, 54, 792-795.
Ohta et al., Chem. Pharm. Bull., 1962, 10, 1260-1261.
Coutts, J. Chem. Soc. C., (1969), 713-716.
Moriconi et al., J. Am. Chem. Soc., 1964, 86, 38-46.
Moriconi et al., J. Org. Chem., 1966, 31, 2090-2098.
Moriconi et al., J. Org. Chem., 1963, 28, 2215-2217.
Chatterjea et al., Leibigs Ann. Chem., 1981, 52-57.
Coutts et al., J. Chem. Soc., 1963, 4610-4612.
Coutts et al., J. Chem. Soc., 1961, 5058-5059.
Eisert, Leibigs Ann. Chem., 1969, 725, 37-51.
Bapat et al., Adv. Heter. Chem., 1969, 10, 199-240.
Corey et al., Journal of the American Chemical Society, 106, 1503-1504.
Radmark et al., 110 FEBS Letters (1980), 213-215.
Morris et al., 19 Prostaglandins (1980), 371-383.
Coutts et al., Meeting Abstract 70 Prostaglandins and Leukotrienes '84.
Walker, Journal of Pharmaceutical Pharmacology, vol. 31, 778-780 (1979).
Samuelsson, Angew. Chem. Int. Ed. Engl. 21 (1982), 902-910.
Green, Tetrahedron, 39 (1983), 1687-1721.
Chatterjea et al., J. Indian Chem. Soc., 1962, 59 (5), 707-9, vol. 97, Chem. Abstracts, p. 805, abstract No. 97:182175u (1982).
Hamana et al., Yakugaku Zasshi, 1975, 95 (1), 87-93 (Japan), abstracted at Chemical Abstracts, vol. 83, 1975, p. 808, abstract No. 9743p (1975).
Tirodkar et al., Curr. Sci., 1972, 41 (18), 679-80, abstracted at vol. 77, Chemical Abstracts, p. 391 (1972), abstract No. 164412b.
Hayashi et al., Yakugaku Zasshi, 1977, 97 (9), 1022-33, abstracted in Chem. Abstracts, vol. 88, Abstract 88:44881j (1978).
Clarkson et al., Chem. Biol. Hydroxamic Acids, 1981, abstracted in Chem. Abstracts, vol. 99, Abstract No. 99:2393f (1983).
Liu et al., J. Chin Chem. Soc., 1975, 22 (4), 317-30, abstracted in Chem. Abstracts, vol. 84, Abstract No. 112457v (1975).
Okamoto et al., Chem. Pharm. Bull., 1971, 19 (9), 1809-14, abstracted in Chem. Abstracts, vol. 75, Abstract 140654q (1971).
Coutts et al., Can. Chem. J., 1970, 48 (15), 2393-2396, abstracted in Chem. Abstracts, vol. 73, Abstract 77022y (1970).
Coutts et al., J. Chem. Soc. C., 1969, 16, 2207-12, abstracted in Chem. Abstracts, vol. 71, Abstract No. 123844(b) (1969).
Yamazaki et al., Yakugaku Zasshi, 1968, 88 (6), 661-4, abstracted in Chem. Abstracts, vol. 69, Abstract 106501d (1968).
Elji, Sci. Papers Inst. Phys. Chem. Res., 56, No. 4, 290-2 (1962), abstracted in Chem. Abstracts, vol. 59, Abstract 2766c (1962).
Masatomo et al., Chem. Pharm. Bull., 10, 51-4 (1962), abstracted in Chem. Abstracts, vol. 58, Abstract 504b (1962).
Motoyoshi et al., Yakugaku Zasshi, 85 (1), 62-6 (1965), abstracted in Chem. Abstracts, vol. 62, abstract 10409d (1965).
Kametani et al., J. Chem. Soc., 1964, 3856-9, abstracted in Chem. Abstracts, vol. 61, abstract 14636 (1964).

Affiliated with

Also associated with

Rating

Lipoxygenase inhibiting compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Lipoxygenase inhibiting compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Lipoxygenase inhibiting compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-711899