Lipoxygenase inhibiting compounds

Details Lipoxygenase inhibiting compounds Lipoxygenase inhibiting compounds

1989-06-02

1991-09-10

Moyer, Donald B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Sulfur containing

568 42, C07C32126, C07B32309, C07B32320

Patent

active

050475932

ABSTRACT:
This invention encompasses a compound of the formula: ##STR1## wherein: R.sub.1 and R.sub.2 are the same or different members of the group consisting of 1,1-dimethylethyl, halo, phenyl and substituted phenyl; Alk is straight or branched chain lower alkylene; R.sub.4 is hydrogen or lower alkyl; R.sub.3 is hydrogen or lower alkyl; or a cycloalkyl group of from 3 to 8 carbon atoms. The formulation of this invention are useful as anti-inflammatory and anti-allergy agents.

REFERENCES:
patent: 4029812 (1977-06-01), Wagner et al.
patent: 4076841 (1978-02-01), Wagner et al.
patent: 4078084 (1978-03-01), Wagner et al.
patent: 4108831 (1978-08-01), Coftman
Chem. Abs. 81, (21) 135705b.
Chem Abs. 82, (18) 112655s.
Chem. Abs. 82 (13) 86292z.
Chem. Abs. 82, (13) 86190q.
Chem. Abs. 82, (13) 86196w.

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