Liposomes containing heparin and a process for obtaining them

Details Liposomes containing heparin and a process for obtaining them Liposomes containing heparin and a process for obtaining them

1977-10-25

1980-12-16

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated to proteinaceous toxin or fragment thereof

424180, 536 21, A01N 4316

Patent

active

042397545

ABSTRACT:
Heparin-based preparations wherein heparin is retained in or on liposomes.
The lipids of said liposomes are preferably phospholipids comprising acyl chains derived from non saturated fatty acids, advantageously essential acids.
These heparin-liposomes preparations have heparinic activity when administered in vivo by the oral route and a delayed-type action.

REFERENCES:
patent: 2055083 (1936-09-01), Klein et al.
patent: 3395222 (1968-07-01), Colescott et al.
patent: 4053585 (1977-10-01), Allison et al.
Chemical Abstracts, vol. 75, (1971), p. 58814h.
Chemical Abstracts, vol. 84, (1976), p. 53732f.

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