Liposomes containing bioavailable iron (II) and process for obta

Details Liposomes containing bioavailable iron (II) and process for obta Liposomes containing bioavailable iron (II) and process for obta

1994-06-24

1996-07-09

Nutter, Nathan M.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424428, 426 89, 426 98, 426 99, 426100, A61K 9127

Patent

active

055342680

ABSTRACT:
Liposomes comprising an iron (II) source selected from the group consisting of ferrous sulfate, ferrous lactate and ferrous citrate. The iron source is stabilized in aqueous solutions of reducing agents, such as, ascorbic acid and soluble ascorbates, which inhibit oxidation of iron (II) to iron (III) and is microencapsulated. A process by which the liposomes containing the iron (II) source are formed is also provided whereby the iron source is encapsulated into an ingestible form.
The liposomes make it possible to increase the level of bioavailable iron in ingestible substrates.

REFERENCES:
patent: 5139803 (1992-08-01), Haynes et al.
patent: 5320906 (1994-06-01), Eley et al.
Lecture by Prof. Richard F. Hurrell entitled "Iron Fortification of Infant Cereals".

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