Liposomes containing active agents aggregated with lipid surfact

Details Liposomes containing active agents aggregated with lipid surfact Liposomes containing active agents aggregated with lipid surfact

1997-02-06

1998-10-27

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424 121, 424 932, 424 951, A61K 9133, A61K 9127

Patent

active

058275339

ABSTRACT:
Liposomes contain active agents which are aggregated with a lipid surfactant. The composition of the liposome membrane stabilizes the membrane against the disruptive effects of the active agent-surfactant aggregate contained therein.

REFERENCES:
patent: 4489056 (1984-12-01), Himmelstein et al.
patent: 4544545 (1985-10-01), Ryan et al.
patent: 4551288 (1985-11-01), Kelly
patent: 4737323 (1988-04-01), Martin et al.
patent: 4752425 (1988-06-01), Martin et al.
patent: 4756910 (1988-07-01), Yagi et al.
patent: 4762915 (1988-08-01), Kung et al.
patent: 4837028 (1989-06-01), Allen
patent: 4839111 (1989-06-01), Huang
patent: 4876094 (1989-10-01), Beaton et al.
patent: 4900556 (1990-02-01), Wheatley et al.
patent: 4906477 (1990-03-01), Kurono et al.
patent: 4920016 (1990-04-01), Allen et al.
patent: 4921757 (1990-05-01), Wheatley et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5023086 (1991-06-01), Wallach
patent: 5160669 (1992-11-01), Wallach et al.
patent: 5213804 (1993-05-01), Martin et al.
patent: 5225212 (1993-07-01), Martin et al.
patent: 5356633 (1994-10-01), Woodle et al.
patent: 5395619 (1995-03-01), Zalipsky et al.
patent: 5527528 (1996-06-01), Allen et al.
patent: 5534241 (1996-07-01), Torchilin et al.
patent: 5534499 (1996-07-01), Ansell
patent: 5622498 (1997-04-01), Brizzolara et al.
patent: 5628936 (1997-05-01), Wallach
patent: 5643600 (1997-07-01), Mathur
Needham, et al.; The Mechanochemistry of Lipid Vesicles Examined by Micropipet Manipulation Techniques, Vesicles, 9:374-439 (1996).
Kenworthy et al.; Range and Magnitude of the Steric Pressure Between Bilayers Containing Phospholipids with Covalently Attached Poly(ethylene glycol), Biophysical Journal, 68:1921-1936 (1995).
Kenworhty et al.; Structure and Phase Behavior of Lipid Suspensions Containing Phospholipids with Covalently Attached Poly(ethylene glycol); Biophysical Journal, 68:1903-1920 (1995).
Mark W. Dewhirst and David Needham; Extravasation of Stealth.RTM. Liposomes Into Tumors: Direct Measurement of Accumulation and Vascular Permeability Using a Skin Flap Window Chamber; Stealth.RTM. Liposomes; Chapter 12:127-137 (1995).
Hayat Alkan-Onyuksel et al.; A Mixed Micellar Formulation Suitable for the Parenteral Administration of Taxol; Pharmaceutical Research; 11(2):206-212 (1994).
D. Needham et al.; Repulsive Interactions and Mechanical Stability of Polymer-Grafted Lipid Membranes; Biochimica et Biophysica Acta; 1108:40-48 (1992).

Affiliated with

Also associated with

Rating

Liposomes containing active agents aggregated with lipid surfact does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Liposomes containing active agents aggregated with lipid surfact, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Liposomes containing active agents aggregated with lipid surfact will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1612073