Liposome targeting using receptor specific ligands

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Lymphokines – e.g. – interferons – interlukins – etc.

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424 851, 424 852, 424450, 530402, 530408, 530409, 530410, A61K 3702, C07K 308, C07K 1508

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active

052584992

ABSTRACT:
Delivery vehicle formulations comprise active agents encapsulated within liposomal vesicles to which are attached protein hormones (ligands) such as interleukin-2. The ligands are capable of showing affinity for specific cell receptors resulting in delivery of the encapsulated active agent to target cells, enabling delivery of active agents to particular cell populations in the treatment of conditions such as immune system disorders.

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Form PCT/ISA/220 mailed Sep. 5, 1989 for Application PCT/EP 89/00521.

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